BDBM596328 US11596633, Compound A

SMILES N[C@@H]1CCCC11CCN(CC1)c1cnc(Sc2ccnc(Cl)c2Cl)c(N)n1

InChI Key InChIKey=PSKJCIJLNDJVDV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 596328   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandPNGBDBM596328(US11596633, Compound A)
Affinity DataIC50: 2.19nMAssay Description:Objective: To demonstrate the inhibition of SHP2 activity with Compounds A, B, and C. Without wishing to be bound by theory, SHP is allosterically ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2023
Entry Details
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