BDBM595713 US11591331, Example 117::US11591331, Example 24

SMILES O=C(NC1CC1)c1ccc(cn1)N1CCN(Cc2cnc3cc(C4CC4)c(=O)[nH]c3c2)CC1

InChI Key InChIKey=GQMZKZHOFLWYAC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 595713   

TargetPoly [ADP-ribose] polymerase 1(Human)
Xinthera

US Patent
LigandPNGBDBM595713(US11591331, Example 24 | US11591331, Example 117)
Affinity DataIC50: 5.20nMAssay Description:Assays based on fluorescent polarization (FP) have been widely utilized in drug discovery due to the homogenous format, robust performance and lack o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Xinthera

US Patent
LigandPNGBDBM595713(US11591331, Example 24 | US11591331, Example 117)
Affinity DataIC50: 2.80E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Xinthera

US Patent
LigandPNGBDBM595713(US11591331, Example 24 | US11591331, Example 117)
Affinity DataIC50: 5.10nMAssay Description:Assays based on fluorescent polarization (FP) have been widely utilized in drug discovery due to the homogenous format, robust performance and lack o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Xinthera

US Patent
LigandPNGBDBM595713(US11591331, Example 24 | US11591331, Example 117)
Affinity DataIC50: 2.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent