BDBM595414 US11590142, Compound 4

SMILES Cn1c2nc(OCCNC[C@@H]3CN(C(=O)O3)c3ccc4OCC(=O)Nc4n3)ccc2ncc1=O

InChI Key InChIKey=AXAOIOFGFFHLAR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 595414   

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
Bugworks Research

US Patent
LigandPNGBDBM595414(US11590142, Compound 4)
Affinity DataIC50: 51nMAssay Description:E. coli gyrase supercoiling and its inhibition was assayed using a kit procured from Inpiralis (K0001) and the protocol (PMID: 2172086) was adapted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bugworks Research

US Patent
LigandPNGBDBM595414(US11590142, Compound 4)
Affinity DataIC50: 3.80E+4nMAssay Description:Compounds were solubilised to 100 mM in DMSO before dilution in HBPS to 300 μM. 6-Point concentration-response curves were generated using 3.16-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent