BDBM595308 US11584714, Compound 1396

SMILES C[C@H](NC(=O)[C@H]1C[C@H](Cc2ccc(cc2)-c2ccc(F)cc2C#N)CN1)C(=O)NCc1ccc(N)nc1C

InChI Key InChIKey=VWTLOABMLWDSOK-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 595308   

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandPNGBDBM595308(US11584714, Compound 1396)
Affinity DataKi: <500nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetMannan-binding lectin serine protease 2(Mouse)
Omeros

US Patent
LigandPNGBDBM595308(US11584714, Compound 1396)
Affinity DataKi: <500nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetProthrombin(Human)
Omeros

US Patent
LigandPNGBDBM595308(US11584714, Compound 1396)
Affinity DataKi: >2.50E+4nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent