BDBM594996 US11584714, Compound 1023::US12195427, Compound 1023::US12351648, Compound 1023

SMILES N[C@H](Cc1ccccc1)C(=O)N1CC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=DVDCELVXBWJPBW-UHFFFAOYSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 594996   

TargetC-type lectin domain family 4 member K(Human)
Omeros

US Patent
LigandPNGBDBM594996(US11584714, Compound 1023 | US12195427, Compound 1...)
Affinity DataIC50: 2.75E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
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TargetProthrombin(Human)
Omeros

US Patent
LigandPNGBDBM594996(US11584714, Compound 1023 | US12195427, Compound 1...)
Affinity DataKi: <500nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
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TargetProthrombin(Human)
Omeros

US Patent
LigandPNGBDBM594996(US11584714, Compound 1023 | US12195427, Compound 1...)
Affinity DataKi: <500nMAssay Description:The thrombin assay utilizes a fluorogenic peptide substrate (Boc-VPR-AMC (R&D Systems) and was run at room temperature in an assay buffer containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

TargetProthrombin(Human)
Omeros

US Patent
LigandPNGBDBM594996(US11584714, Compound 1023 | US12195427, Compound 1...)
Affinity DataKi: <500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
Go to US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandPNGBDBM594996(US11584714, Compound 1023 | US12195427, Compound 1...)
Affinity DataKi:  1.50E+3nMAssay Description:The assay was run at room temperature in an assay buffer containing 20 mM Hepes, pH 7.4, 140 mM NaCl and 0.1% Tween 20. Assay parameters were adjuste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandPNGBDBM594996(US11584714, Compound 1023 | US12195427, Compound 1...)
Affinity DataKi:  1.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
Go to US Patent

TargetMannan-binding lectin serine protease 2(Human)
Omeros

US Patent
LigandPNGBDBM594996(US11584714, Compound 1023 | US12195427, Compound 1...)
Affinity DataKi: <2.50E+3nMAssay Description:The MASP-2 assay protocol was carried out as follows. Test compounds were serially diluted in DMSO and then 100 nL of each dilution was transferred t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent