BDBM594959 US11584758, Compound I-45

SMILES CN1c2nc(ccc2OC[C@H](NC(=O)c2cc(Oc3ccccc3)ccn2)C1=O)C#CC(F)(F)C1COC1

InChI Key InChIKey=IADQFWSWSAKNNP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 594959   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM594959(US11584758, Compound I-45)
Affinity DataIC50: 59.8nMAssay Description:In this example, compounds of the disclosure were evaluated using a biochemical assay using the ADP-Glo technology. ADP-Glo (Promega, Madison, Wis., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent