BDBM594918 US11584758, Compound I-4

SMILES C[C@H]1Oc2cccnc2N(C)C(=O)[C@H]1N1CCc2c(Cl)n(Cc3ccccc3)nc2C1=O

InChI Key InChIKey=UIIHHPHUPMMECJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 594918   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM594918(US11584758, Compound I-4)
Affinity DataIC50: 22.9nMAssay Description:In this example, compounds of the disclosure were evaluated using a biochemical assay using the ADP-Glo technology. ADP-Glo (Promega, Madison, Wis., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent