BDBM594859 US11584755, Example 148

SMILES OC(=O)c1c(O)c(=O)n(Cc2cn(nn2)-c2ccc3OCOc3c2)c2ccsc12

InChI Key InChIKey=OZTVLWUETLVKMG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 594859   

TargetFlap endonuclease 1(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM594859(US11584755, Example 148)
Affinity DataIC50: 200nMAssay Description:FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetExonuclease 1(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM594859(US11584755, Example 148)
Affinity DataIC50: 500nMAssay Description:FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetDNA excision repair protein ERCC-5(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM594859(US11584755, Example 148)
Affinity DataIC50: 500nMAssay Description:FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent