BDBM594712 8-(Pyrazolo[1,5-a]pyridine-3-carbonyl)-2,8-diazaspiro[4.5]decane-1,3-dione::US11584748, Example 79

SMILES O=C(N1CCC2(CC(=O)NC2=O)CC1)c1cnn2ccccc12

InChI Key InChIKey=FIHHIXWGSKFVKE-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 594712   

TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594712(8-(Pyrazolo[1,5-a]pyridine-3-carbonyl)-2,8-diazasp...)
Affinity DataKd:  28nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent