BDBM594701 8-(Thiazolo[4,5-b]pyridin-2-yl)-2,8-diazaspiro[4.5]decane-1,3-dione::US11584748, Example 68

SMILES O=C1CC2(CCN(CC2)c2nc3ncccc3s2)C(=O)N1

InChI Key InChIKey=PQWDONLBEMBXRA-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 594701   

TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594701(8-(Thiazolo[4,5-b]pyridin-2-yl)-2,8-diazaspiro[4.5...)
Affinity DataKd:  16nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent