BDBM594691 (S)-8-(1,2,3,4-Tetrahydronaphthalene-1-carbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione::US11584748, Example 58

SMILES O=C([C@H]1CCCc2ccccc12)N1CCC2(CC1)NC(=O)NC2=O

InChI Key InChIKey=AQBJULSTCREMNI-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 594691   

TargetProtein cereblon(Human)
C4 Therapeutics

US Patent
LigandPNGBDBM594691((S)-8-(1,2,3,4-Tetrahydronaphthalene-1-carbonyl)-1...)
Affinity DataKd:  4nMAssay Description:Determination of the affinities of compounds to protein containing one or more tryptophan is measurable by monitoring the fluorescence emission in di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent