BDBM594202 US11584746, Compound I-19

SMILES Fc1ccc2Nc3ccc(cc3C(=O)N(Cc3ccc4cc[nH]c4c3)c2c1)-c1ccc(cc1)N1CCNCC1

InChI Key InChIKey=YZRYOVKCTGMOHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 594202   

TargetEpidermal growth factor receptor [T790M,L858R](Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM594202(US11584746, Compound I-19)
Affinity DataIC50: 1.00E+4nMAssay Description:IC50 values were determined at both 1 μM and 1 mM ATP to identify both ATP competitive and non-competitive compounds. Hits were also counter-scr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent