BDBM594191 3-[6-(5-fluoropyridin-2-::US11584732, Example 25

SMILES OCc1cc(cc(c1)-c1cc(ncn1)-c1ccc(F)cn1)C#N

InChI Key InChIKey=SRGZSMLWULJFQY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 594191   

TargetMetabotropic glutamate receptor 5(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM594191(3-[6-(5-fluoropyridin-2- | US11584732, Example 25)
Affinity DataKi:  4.27nMAssay Description:After thawing, membrane homogenates were re-suspended in the binding buffer (50 mM HEPES pH 7.5, 150 mM NaCl) to a final assay concentration of 2.5 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent