BDBM593952 US11583532, Example 3.3

SMILES Cc1nc2ncnn2c(N)c1Cc1ccc(c(n1)N1CC(F)(F)C1)C(F)(F)F

InChI Key InChIKey=LAEOLJHRNRBLMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 593952   

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM593952(US11583532, Example 3.3)
Affinity DataIC50: 0.320nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM593952(US11583532, Example 3.3)
Affinity DataIC50: 0.760nMAssay Description:Methods: Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent