BDBM593795 US11578084, Compound I-078

SMILES Cc1nc(CC(=O)N[C@H]2CC[C@](F)(CCN3CCc4ccc(OCC(C)(F)F)nc4CC3)CC2)no1

InChI Key InChIKey=KRNLFYUCQHYKNH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 593795   

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM593795(US11578084, Compound I-078)
Affinity DataKi:  0.130nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.6HO (20909-55, Nacal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM593795(US11578084, Compound I-078)
Affinity DataKi: >1.80E+3nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.06HO (20909-55, Naca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent