BDBM593789 US11578084, Compound I-072

SMILES CN1Cc2c(cccc2C(=O)N[C@H]2CC[C@](F)(CCN3CCc4nc(OCC(F)F)sc4CC3)CC2)C1=O

InChI Key InChIKey=AXGNSCJOHWKGNC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 593789   

TargetD(3) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM593789(US11578084, Compound I-072)
Affinity DataKi:  0.130nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.6HO (20909-55, Nacal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent

TargetD(2) dopamine receptor(Human)
Shionogi

US Patent
LigandPNGBDBM593789(US11578084, Compound I-072)
Affinity DataKi: >1.70E+3nMAssay Description:Buffer solution: 50 mM Tris-HCl (35409-45, Nacalai Tesque) (pH 7.4) containing 120 mM NaCl (31320-05, Nacalai Tesque), 1 mM MgCl.06HO (20909-55, Naca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent