BDBM593677 2'-(2-hydroxy-7,7-dimethyl-1'H,7H- spiro[furo[3,4-b]pyridine-5,4'- piperidin]-1'-yl)-1,3-dihydro-4'H- spiro[indene-2,5'-[1,3]oxazol]-4'-one::US11578077, Example 72

SMILES CC1(C)OC2(CCN(CC2)C2=NC(=O)C3(Cc4ccccc4C3)O2)c2ccc(O)nc12

InChI Key InChIKey=PDZJYQFMHQCMDB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593677   

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM593677(US11578077, Example 72 | 2'-(2-hydroxy-7,7-dimethy...)
Affinity DataKi:  3.16nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
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Date in BDB:
3/31/2023
Entry Details
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