BDBM593674 2'-(7,7-dimethyl-1'H,7H- spiro[furo[3,4-b]pyridine-5,4'- piperidin]-1'-yl)-4-hydroxy-1,3- dihydro-4'H-spiro[indene-2,5'- [1,3]oxazol]-4'-one::US11578077, Example 69

SMILES CC1(C)OC2(CCN(CC2)C2=NC(=O)C3(Cc4cccc(O)c4C3)O2)c2cccnc12

InChI Key InChIKey=JDTYEDBJFSWAJC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593674   

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM593674(US11578077, Example 69 | 2'-(7,7-dimethyl-1'H,7H- ...)
Affinity DataKi:  0.501nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent