BDBM593673 2'-(7,7-dimethyl-1'H,7H- spiro[furo[3,4-b]pyridine-5,4'- piperidin]-1'-yl)-4-methoxy-1,3- dihydro-4'H-spiro[indene-2,5'- [1,3]oxazol]-4'-one::US11578077, Example 68

SMILES COc1cccc2CC3(Cc12)OC(=NC3=O)N1CCC2(CC1)OC(C)(C)c1ncccc21

InChI Key InChIKey=GTFKMBIFBISDPN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593673   

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM593673(US11578077, Example 68 | 2'-(7,7-dimethyl-1'H,7H- ...)
Affinity DataKi:  7.94nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
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Date in BDB:
3/31/2023
Entry Details
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