BDBM593672 1'-[4'-oxo-3,4-dihydro-1H,4'H- spiro[naphthalene-2,5'-[1,3]oxazol]- 2'-yl]-1'H,3H-spiro[2-benzofuran- 1,4'-piperidin]-3-one enantiomer B::US11578077, Example 67

SMILES O=C1OC2(CCN(CC2)C2=NC(=O)[C@@]3(CCc4ccccc4C3)O2)c2ccccc12

InChI Key InChIKey=FPIXNIUKJJJUCH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593672   

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM593672(US11578077, Example 67 | 1'-[4'-oxo-3,4-dihydro-1H...)
Affinity DataKi:  3.98nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
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Date in BDB:
3/31/2023
Entry Details
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