BDBM593666 2'-(1'H,3H-spiro[2-benzofuran-1,4'- piperidin]-1'-yl)-3-(trifluoromethyl)- 5,7-dihydro-4'H- spiro[cyclopenta[c]pyridine-6,5'- [1,3]oxazol]-4'-one::US11578077, Example 61

SMILES FC(F)(F)c1cc2CC3(Cc2cn1)OC(=NC3=O)N1CCC2(CC1)OCc1ccccc21

InChI Key InChIKey=TWJNVDOEEQYTBV-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593666   

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM593666(US11578077, Example 61 | 2'-(1'H,3H-spiro[2-benzof...)
Affinity DataKi:  3.16nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
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Date in BDB:
3/31/2023
Entry Details
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