BDBM593661 2'-(1'H,3H-spiro[2-benzofuran-1,4'- piperidin]-1'-yl)-5,7-dihydro-4'H- spiro[cyclopenta[b]pyridine-6,5'- [1,3]oxazol]-4'-one::US11578077, Example 56

SMILES O=C1N=C(OC11Cc2cccnc2C1)N1CCC2(CC1)OCc1ccccc21

InChI Key InChIKey=WRPWMTMTOKRZIS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593661   

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM593661(US11578077, Example 56 | 2'-(1'H,3H-spiro[2-benzof...)
Affinity DataKi:  6.31nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent