BDBM593657 2'-(3-methyl-1'H,7H-spiro[furo[3,4- b]pyridine-5,4'-piperidin]-1'-yl)-1,3- dihydro-4'H-spiro[indene-2,5'- [1,3]oxazol]-4'-one::US11578077, Example 52

SMILES Cc1cnc2COC3(CCN(CC3)C3=NC(=O)C4(Cc5ccccc5C4)O3)c2c1

InChI Key InChIKey=XDTDMKOTTAGPEU-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593657   

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM593657(US11578077, Example 52 | 2'-(3-methyl-1'H,7H-spiro...)
Affinity DataKi:  5.01nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
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Date in BDB:
3/31/2023
Entry Details
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