BDBM593651 2'-(6-methyl-1H,1'H-spiro[furo[3,4- c]pyridine-3,4'-piperidin)-1'-yl)-1,3- dihydro-4'H-spiro[indene-2,5'- [1,3]oxazol]-4'-one::US11578077, Example 46

SMILES Cc1cc2COC3(CCN(CC3)C3=NC(=O)C4(Cc5ccccc5C4)O3)c2cn1

InChI Key InChIKey=QKHJGKGQLVGEIA-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593651   

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM593651(2'-(6-methyl-1H,1'H-spiro[furo[3,4- c]pyridine-3,4...)
Affinity DataKi:  3.16nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
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Date in BDB:
3/31/2023
Entry Details
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