BDBM593648 2-methyl-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene-2,5'-[1,3]oxazol]-2'-yl)- 5H-spiro[furo[3,4-b]pyridine-7,4'- piperidin]-5-one::US11578077, Example 43

SMILES Cc1ccc2C(=O)OC3(CCN(CC3)C3=NC(=O)C4(Cc5ccccc5C4)O3)c2n1

InChI Key InChIKey=KZTKMTHDCCLUGD-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593648   

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM593648(2-methyl-1'-(4'-oxo-1,3-dihydro-4'H- spiro[indene-...)
Affinity DataKi:  5.01nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
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Date in BDB:
3/31/2023
Entry Details
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