BDBM593641 2'-(1'H,5H-spiro[furo[3,4-b]pyridine- 7,4'-piperidin]-1'-yl)-1,3-dihydro-4'H- spiro[indene-2,5'-[1,3]oxazol]-4'-one::US11578077, Example 36

SMILES O=C1N=C(OC11Cc2ccccc2C1)N1CCC2(CC1)OCc1cccnc21

InChI Key InChIKey=XVJSWQOUQQFYCV-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593641   

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent

LigandBDBM593641(2'-(1'H,5H-spiro[furo[3,4-b]pyridine- 7,4'-piperid...)Copy SMILESCopy InChI

Affinity DataKi:  2.51nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/31/2023
Entry Details
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