BDBM593633 1'-(5-hydroxy-4'-oxo-1,3-dihydro-4'H- spiro[indene-2,5'-[1,3]oxazol]-2'-yl)- 3H-spiro[2-benzofuran-1,4'-piperidin]- 3-one::US11578077, Example 28

SMILES Oc1ccc2CC3(Cc2c1)OC(=NC3=O)N1CCC2(CC1)OC(=O)c1ccccc21

InChI Key InChIKey=YDPQSPMEGDXLGE-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593633   

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM593633(1'-(5-hydroxy-4'-oxo-1,3-dihydro-4'H- spiro[indene...)
Affinity DataKi:  3.98nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
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