BDBM593629 (-)-1'-[5-methyl-4'-oxo-1,3-dihydro- 4'H-spiro[indene-2,5',-[1,3]oxazol]-2'- yl]-3H-spiro[2-benzofuran-1,4'- piperidin]-3-one::US11578077, Example 24

SMILES Cc1ccc2C[C@@]3(Cc2c1)OC(=NC3=O)N1CCC2(CC1)OC(=O)c1ccccc21

InChI Key InChIKey=XSUMOXKLQDPUKC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593629   

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM593629((-)-1'-[5-methyl-4'-oxo-1,3-dihydro- 4'H-spiro[ind...)
Affinity DataKi:  2.51nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
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