BDBM593622 6-chloro-1'-(4-oxo-1,3-dihydro-4'H- spiro[indene-2,5'-[1,3]oxazol]-2'-yl)- 3H-spiro[2-benzofuran-1,4'-piperidin]- 3-one::US11578077, Example 17

SMILES Clc1ccc2C(=O)OC3(CCN(CC3)C3=NC(=O)C4(Cc5ccccc5C4)O3)c2c1

InChI Key InChIKey=GVZRRQFOZKJMSB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593622   

TargetVasopressin V1a receptor(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM593622(6-chloro-1'-(4-oxo-1,3-dihydro-4'H- spiro[indene-2...)
Affinity DataKi:  2.51nMAssay Description:The human V1a receptor was cloned by RT-PCR from total human liver RNA. The coding sequence was subcloned in an expression vector after sequencing to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent