BDBM593592 4-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-1- (2-(3,5-difluorophenoxy)ethyl)pyridin-2(1H)- one::US11578066, Compound II-14

SMILES FC(F)c1nnc(o1)-c1ccn(CCOc2cc(F)cc(F)c2)c(=O)c1

InChI Key InChIKey=YPKQCLGINZNOAZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593592   

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593592(US11578066, Compound II-14 | 4-(5-(difluoromethyl)...)
Affinity DataIC50: 3nMAssay Description:The compounds disclosed herein were tested for potency against HDAC6 and selectivity against HDAC1 in a biochemical assay. A biochemical assay was ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
Go to US Patent