BDBM593510 N-(5-chloropyridin-3-yl)-N-({5-[5- (difluoromethyl)-1,3,4-oxadiazol-2-yl]-1,3- thiazol-2-yl}methyl)-2-[(2S)-2- methylmorpholin-4-yl]ethane-1-sulfonamide::US11578066, Compound I-202::US20230381148, Compound I-202::US20240269137, Compound I-202
SMILES C[C@H]1CN(CCS(=O)(=O)N(Cc2ncc(s2)-c2nnc(o2)C(F)F)c2cncc(Cl)c2)CCO1
InChI Key InChIKey=JCXFQKCTNIUUNJ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 593510
Affinity DataIC50: 12.7nMAssay Description:Table 13: The compounds disclosed herein, in particular those of Formula (I), were synthesized according to methods disclosed in PCT/US2020/066439, p...More data for this Ligand-Target Pair
Affinity DataIC50: 12.7nMAssay Description:The compounds disclosed herein were tested for potency against HDAC6 and selectivity against HDAC1 in a biochemical assay. A biochemical assay was ad...More data for this Ligand-Target Pair
Affinity DataIC50: 12.7nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair