BDBM593466 N-(5-chloropyridin-3-yl)-2-cyano-N-({5-[5- (difluoromethyl)-1,3,4-oxadiazol-2-yl]-1,3- thiazol-2-yl}methyl)ethane-1-sulfonamide::US11578066, Compound I-158::US20230381148, Compound I-158::US20240269137, Compound I-158
SMILES FC(F)c1nnc(o1)-c1cnc(CN(c2cncc(Cl)c2)S(=O)(=O)CCC#N)s1
InChI Key InChIKey=RBHQRNLLYVTQSL-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 593466
Affinity DataIC50: 7.22nMAssay Description:Table 13: The compounds disclosed herein, in particular those of Formula (I), were synthesized according to methods disclosed in PCT/US2020/066439, p...More data for this Ligand-Target Pair
Affinity DataIC50: 7.22nMAssay Description:The compounds disclosed herein were tested for potency against HDAC6 and selectivity against HDAC1 in a biochemical assay. A biochemical assay was ad...More data for this Ligand-Target Pair
Affinity DataIC50: 7.22nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair