BDBM593421 N-[5-(1,1-difluorethyl)pyridin-3-yl]-N-({5- [5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-1,3- thiazol-2-yl}methyl)ethane-1-sulfonamide::US11578066, Compound I-112::US20230381148, Compound I-112::US20240269137, Compound I-112
SMILES CCS(=O)(=O)N(Cc1ncc(s1)-c1nnc(o1)C(F)F)c1cncc(c1)C(C)(F)F
InChI Key InChIKey=XWRRGTHMIASNSY-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 593421
Affinity DataIC50: 10.1nMAssay Description:Table 13: The compounds disclosed herein, in particular those of Formula (I), were synthesized according to methods disclosed in PCT/US2020/066439, p...More data for this Ligand-Target Pair
Affinity DataIC50: 10.1nMAssay Description:The compounds disclosed herein were tested for potency against HDAC6 and selectivity against HDAC1 in a biochemical assay. A biochemical assay was ad...More data for this Ligand-Target Pair
Affinity DataIC50: 10.1nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair