BDBM592997 US11578054, Example 1019

SMILES C[C@](CO)(NCc1cc(Cl)c(OC2CCc3c2cccc3-c2cccc(OCCCNC[C@H](O)CO)c2Cl)cc1OCc1cncc(c1)C#N)C(O)=O

InChI Key InChIKey=XPBVISYFOLVBDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592997   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM592997(US11578054, Example 1019)
Affinity DataIC50: 2.5nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent