BDBM592973 US11578054, Example 1003

SMILES CN1CCCC(COc2cccc(c2Cl)-c2cccc3C(CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CO)cc2Cl)C1

InChI Key InChIKey=UGJDRTUHUNQUAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592973   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM592973(US11578054, Example 1003)
Affinity DataIC50: 9.10nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent