BDBM592805 (1S,4R,5S)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-2-(3,5- dichlorophenyl)-2-azabicyclo[3.1.0]hexane-4- carboxamide::US11572374, Example 15-12-2

SMILES Clc1cc(Cl)cc(c1)N1C[C@@H]([C@@H]2C[C@H]12)C(=O)N[C@@H]1C[C@@H]2CC[C@H]1N2C#N

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592805   

LigandPNGBDBM592805(US11572374, Example 15-12-2 | (1S,4R,5S)-N-((1R,2R...)
Affinity DataIC50: 48nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
Go to US Patent