BDBM592779 (3E)-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-4-(2,5- dichlorophenyl)-3-butenamide::US11572374, Example 12-25

SMILES Clc1ccc(Cl)c(\C=C\CC(=O)N[C@@H]2C[C@@H]3CC[C@H]2N3C#N)c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592779   

LigandPNGBDBM592779(US11572374, Example 12-25 | (3E)-N-((1R,2R,4S)-7-c...)
Affinity DataIC50: 26nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
Go to US Patent