BDBM592777 (3E)-4-(3-chlorophenyl)-N-((1R,2R,4S)-7- cyano-7-azabicyclo[2.2.1]heptan-2-yl)-3- butenamide::US11572374, Example 12-23

SMILES Clc1cccc(\C=C\CC(=O)N[C@@H]2C[C@@H]3CC[C@H]2N3C#N)c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592777   

LigandPNGBDBM592777(US11572374, Example 12-23 | (3E)-4-(3-chlorophenyl...)
Affinity DataIC50: 54nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
Go to US Patent