BDBM592764 N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1]heptan-2-yl)-3-(2,5- dichlorophenyl)cyclopentanecarboxamide::US11572374, Example 12-10::US11572374, Example 12-30

SMILES Clc1ccc(Cl)c(c1)C1CCC(C1)C(=O)N[C@@H]1C[C@@H]2CC[C@H]1N2C#N

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 592764   

LigandPNGBDBM592764(US11572374, Example 12-10 | US11572374, Example 12...)
Affinity DataIC50: 64nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
Go to US Patent

LigandPNGBDBM592764(US11572374, Example 12-10 | US11572374, Example 12...)
Affinity DataIC50: 270nMAssay Description:USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
Go to US Patent