BDBM592358 US11572368, Compound 35

SMILES CC(=O)N1CCC(CC1)C(=O)Nc1cc(ccc1N)-c1cccs1

InChI Key InChIKey=AOWNNPKBATYOEX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 592358   

TargetHistone deacetylase 1(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM592358(US11572368, Compound 35)
Affinity DataIC50: 11nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM592358(US11572368, Compound 35)
Affinity DataIC50: 49nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM592358(US11572368, Compound 35)
Affinity DataIC50: 50nMAssay Description:HDAC2: The following trypsin-coupled protocol and Caliper protocol described Herein was used to assay the compounds of the invention. HDAC2-Kinetic I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM592358(US11572368, Compound 35)
Affinity DataIC50: 50nMAssay Description:HDAC1: The following trypsin-coupled protocol and Caliper protocol described Herein was used to assay the compounds of the invention. Trypsin Coupled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
The General Hospital

US Patent
LigandPNGBDBM592358(US11572368, Compound 35)
Affinity DataIC50: 3.05E+3nMAssay Description:HDAC3: The following trypsin-coupled protocol and Caliper protocol described Herein was used to assay the compounds of the invention. HDAC3-Kinetic I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent