BDBM592332 (2S)-1-{[2-[2-cyano-3-(2,3-dihydro-1,4-benzodioxin-6-yl)phenyl]-6-(cyanomethoxy)-1,3-benzoxazol-5-yl]methyl}piperidine-2-carboxylic Acid::US11572366, Example 37

SMILES OC(=O)[C@@H]1CCCCN1Cc1cc2nc(oc2cc1OCC#N)-c1cccc(-c2ccc3OCCOc3c2)c1C#N

InChI Key InChIKey=WXOGJKHSKFQFGH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592332   

LigandPNGBDBM592332((2S)-1-{[2-[2-cyano-3-(2,3-dihydro-1,4-benzodioxin...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent