BDBM592331 (2S)-1-({6-(cyanomethoxy)-2-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]-1,3-benzoxazol-5-yl}methyl)piperidine-2-carboxylic Acid::US11572366, Example 36

SMILES Cc1c(cccc1-c1ccc2OCCOc2c1)-c1nc2cc(CN3CCCC[C@H]3C(O)=O)c(OCC#N)cc2o1

InChI Key InChIKey=ZXGOOJXOOLGUEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592331   

LigandPNGBDBM592331((2S)-1-({6-(cyanomethoxy)-2-[3-(2,3-dihydro-1,4-be...)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent