BDBM592330 (2S)-1-({6-(cyanomethoxy)-2-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-methylpyridin-2-yl]-1,3-benzoxazol-5-yl}methyl)piperidine-2-carboxylic Acid::US11572366, Example 35

SMILES Cc1c(ccnc1-c1nc2cc(CN3CCCC[C@H]3C(O)=O)c(OCC#N)cc2o1)-c1ccc2OCCOc2c1

InChI Key InChIKey=GHQBAIJMISZATI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592330   

LigandPNGBDBM592330((2S)-1-({6-(cyanomethoxy)-2-[4-(2,3-dihydro-1,4-be...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
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Date in BDB:
3/26/2023
Entry Details
US Patent