BDBM592312 (2S)-1-({2-[2-cyano-3-(2,3-dihydro-1,4-benzodioxin-6-yl)phenyl]-7-methyl-1,3-benzoxazol-5-yl}methyl)piperidine-2-carboxylic Acid::US11572366, Example 17

SMILES Cc1cc(CN2CCCC[C@H]2C(O)=O)cc2nc(oc12)-c1cccc(-c2ccc3OCCOc3c2)c1C#N

InChI Key InChIKey=IRAOBULKNPMMHM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592312   

LigandPNGBDBM592312((2S)-1-({2-[2-cyano-3-(2,3-dihydro-1,4-benzodioxin...)
Affinity DataIC50: 55nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent