BDBM592205 US11572353, Compound 19

SMILES CNC(=O)c1ccc(Cl)c(c1)C#Cc1nn([C@H]2CCN(C2)C(=O)C=C)c(N)c1C(N)=O

InChI Key InChIKey=ABBKDRAIZOTGKP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 592205   

TargetFibroblast growth factor receptor 1(Human)
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM592205(US11572353, Compound 19)
Affinity DataIC50: 10nMAssay Description:The reaction buffer contains the following components: 5-fold diluted enzymatic buffer/kinase 5x(Cisbio, Cat No. 62EZBFDD)(its main component is 50nM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM592205(US11572353, Compound 19)
Affinity DataIC50: 10nMAssay Description:The reaction buffer contains the following components: 5-fold diluted enzymatic buffer/kinase 5x(Cisbio, Cat No. 62EZBFDD)(its main component is 50nM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM592205(US11572353, Compound 19)
Affinity DataIC50: 10nMAssay Description:The reaction buffer contains the following components: 5-fold diluted enzymatic buffer/kinase 5x(Cisbio, Cat No. 62EZBFDD)(its main component is 50nM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM592205(US11572353, Compound 19)
Affinity DataIC50: 10nMAssay Description:The reaction buffer contains the following components: 5-fold diluted enzymatic buffer/kinase 5x(Cisbio, Cat No. 62EZBFDD)(its main component is 50nM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent