BDBM592204 US11572353, Compound 18

SMILES NC(=O)c1c(N)n(nc1C#Cc1cc(Cl)ccc1F)[C@H]1CCN(C1)C(=O)C=C

InChI Key InChIKey=XJTGHJBDGZJXGP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 592204   

TargetFibroblast growth factor receptor 2(Human)
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM592204(US11572353, Compound 18)
Affinity DataIC50: 10nMAssay Description:The reaction buffer contains the following components: 5-fold diluted enzymatic buffer/kinase 5x(Cisbio, Cat No. 62EZBFDD)(its main component is 50nM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM592204(US11572353, Compound 18)
Affinity DataIC50: 55nMAssay Description:The reaction buffer contains the following components: 5-fold diluted enzymatic buffer/kinase 5x(Cisbio, Cat No. 62EZBFDD)(its main component is 50nM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 4(Human)
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM592204(US11572353, Compound 18)
Affinity DataIC50: 55nMAssay Description:The reaction buffer contains the following components: 5-fold diluted enzymatic buffer/kinase 5x(Cisbio, Cat No. 62EZBFDD)(its main component is 50nM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Beijing Innocare Pharma Tech

US Patent
LigandPNGBDBM592204(US11572353, Compound 18)
Affinity DataIC50: 55nMAssay Description:The reaction buffer contains the following components: 5-fold diluted enzymatic buffer/kinase 5x(Cisbio, Cat No. 62EZBFDD)(its main component is 50nM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent