BDBM592069 US11566028, Example 8

SMILES CNC(=O)c1cc(cc(c1)-c1cnn2cc(-c3cnn(C)c3)c(N[C@H]3CCOC3)nc12)C#N

InChI Key InChIKey=NKFXDCIWGHYBJE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 592069   

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM592069(US11566028, Example 8)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2023
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM592069(US11566028, Example 8)
Affinity DataIC50: 115nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2023
Entry Details
Go to US Patent