BDBM592065 US11566028, Example 4

SMILES CNC(=O)c1cc(C)c(F)c(c1)-c1cnn2cc(-c3cnn(C)c3)c(OC3CCOC3)nc12

InChI Key InChIKey=SIWLVOKRZCQNMV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 592065   

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM592065(US11566028, Example 4)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2023
Entry Details
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TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM592065(US11566028, Example 4)
Affinity DataIC50: 115nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2023
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM592065(US11566028, Example 4)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2023
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 4(Human)
Incyte

US Patent
LigandPNGBDBM592065(US11566028, Example 4)
Affinity DataIC50: 115nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2023
Entry Details
Go to US Patent