BDBM591169 2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7-fluoroisoquinolin- 3-yl)amino)-5,5,6-trimethyl-5,6- dihydro-4H-pyrazolo[1,5- d][1,4]diazepin-7(8H)-one::US11566003, Compound 235

SMILES CN1C(=O)Cn2nc(Nc3cc4cc(c(F)c(N)c4cn3)-c3cncc(N)c3C)cc2CC1(C)C

InChI Key InChIKey=KBIMNGQKPKBVKG-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 591169   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Genentech

US Patent

LigandBDBM591169(2-((8-amino-6-(5-amino-4- methylpyridin-3-yl)-7-fl...)Copy SMILESCopy InChI

Affinity DataKi:  0.0240nMAssay Description:To a 384 well Proxiplate with 80 nL compound or DMSO spotted on was added 4 μl/well kinase mix. The mixture was preincubated for 30 minutes and ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/19/2023
Entry Details
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