BDBM591117 US11566003, Compound 209::trans-N-(8-amino-6-(5-amino-4- methylpyridin-3-yl)-7- chloroisoquinolin-3-yl)-2- (cyanomethyl)cyclopropane-1- carboxamide

SMILES Cc1c(N)cncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3CC#N)ncc2c(N)c1Cl

InChI Key InChIKey=PREUWBOKUNFNFD-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 591117   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Genentech

US Patent

LigandBDBM591117(trans-N-(8-amino-6-(5-amino-4- methylpyridin-3-yl)...)Copy SMILESCopy InChI

Affinity DataKi:  0.0410nMAssay Description:For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/19/2023
Entry Details
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